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Started by PLEASEHELP1991, October 26, 2014, 10:37:29 AM

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PLEASEHELP1991

October 26, 2014, 10:37:29 AM Last Edit: October 26, 2014, 02:03:28 PM by PLEASEHELP1991
        In 2008, approximately one in five Human Immunodeficiency Virus (HIV)-positive persons over 13 years old in the United States were not aware of their HIV status (Chan). HIV prevention initiatives like early testing can save lives due to early antiretroviral treatment and have the potential to reduce further HIV transmission. Although rapid HIV tests and HIV laboratory tests share a similar biological basis, there are a few distinctions between the two kinds of testing.

   One distinction between rapid HIV testing and HIV laboratory testing is the amount of training required to perform the test. Rapid HIV tests like OraQuick Advance are Clinical Laboratory Improvement Amendments (CLIA)-waived; in other words, persons performing the test do not have to perform it in a laboratory and do not need extensive training to perform the test (“OraSure”). Laboratory HIV tests can only be performed on collected blood or urine samples in a laboratory setting. Consequently, rapid HIV tests can be performed at critical outreach settings such as sex venues and bars at lower cost than traditional laboratory HIV testing.

   Another distinction between rapid HIV testing and laboratory HIV tests is the time to receive results. A common rapid HIV test like the OraQuick Advance takes only twenty minutes for a reliable result (“OraSure”). This may help reduce anxiety surrounding the test; and if performed at the point of care, there is an increased likelihood that the person being tested will receive their result (Advantages and disadvantages of different kinds of FDA-approved HIV immunoassays). The OraQuick Advance test, however, has more false positives; that is, it has lower specificity than the traditional laboratory HIV antibody test. Laboratory tests for HIV can take up to two weeks to report results, as initially positive laboratory antibody tests are confirmed with a confirmatory test (“Human”).

   A very important distinction between rapid HIV testing and laboratory testing is their window period. The stated window period, the period when the body doesn’t make detectable antibodies to HIV, of the OraQuick Advance test is three months (“OraSure”). Testing sooner than the window period can lead to false negative results. Laboratory HIV tests like Ribonucleic Acid (RNA) testing that test for actual viral material instead of the body’s reaction to the virus can detect infection with HIV as soon as three weeks (“HIV”).

   There are advantages and disadvantages to each kind of HIV testing. If one has had recent unprotected anal or vaginal sex, testing at four weeks with a laboratory test such as an RNA test or a fourth-generation ELISA is recommended. If one has had protected sex or has limited means, a rapid HIV test taken every three months should suffice.
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Quote from: PLEASEHELP1991 on October 26, 2014, 10:37:29 AM
        In 2008, approximately one in five Human Immunodeficiency Virus (HIV)-positive persons over 13 years old in the United States were not aware of their HIV status (Chan). HIV prevention initiatives like early testing can save lives due to early antiretroviral treatment and have the potential to reduce further HIV transmission. Although rapid HIV tests and HIV laboratory tests share a similar biological basis, there are a few distinctions between the two kinds of testing.

   One distinction between rapid HIV testing and HIV laboratory testing is the amount of training required to perform the test. Rapid HIV tests like OraQuick Advance are Clinical Laboratory Improvement Amendments (CLIA)-waived; in other words, persons performing the test do not have to perform it in a laboratory and do not need extensive training to perform the test (“OraSure”). Laboratory HIV tests can only be performed on collected blood or urine samples in a laboratory setting. Consequently, rapid HIV tests can be performed at critical outreach settings such as sex venues and bars at lower cost than traditional laboratory HIV testing.

   Another distinction between rapid HIV testing and laboratory HIV tests is the time to receive results. A common rapid HIV test like the OraQuick Advance takes only twenty minutes for a reliable result (“OraSure”). This may help reduce anxiety surrounding the test; and if performed at the point of care, there is an increased likelihood that the person being tested will receive their result (Advantages and disadvantages of different kinds of FDA-approved HIV immunoassays). The OraQuick Advance test, however, has more false positives; that is, it has lower specificity than the traditional laboratory HIV antibody test. Laboratory tests for HIV can take up to two weeks to report results, as initially positive laboratory antibody tests are confirmed with a confirmatory test (“Human”).

   A very important distinction between rapid HIV testing and laboratory testing is their window period. The stated window period, the period when the body doesn’t make detectable antibodies to HIV, of the OraQuick Advance test is three months (“OraSure”). Testing sooner than the window period can lead to false negative results. Laboratory HIV tests like Ribonucleic Acid (RNA) testing that test for actual viral material instead of the body’s reaction to the virus can detect infection with HIV as soon as three weeks (“HIV”).

   There are advantages and disadvantages to each kind of HIV testing. If one has had recent unprotected anal or vaginal sex, testing at four weeks with a laboratory test such as an RNA test or a fourth-generation ELISA is recommended. If one has had protected sex or has limited means, a rapid HIV test taken every three months should suffice.

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